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High Purity Tianeptine Sodium
Tianeptine Sodium
CAS-No.:30123-17-2
Formula: C21H24ClN2NaO4S
Formula Weight: 458.93
Introduction of Tianeptine sodium salt:
Tianeptine sodium salt is a salt of Tianeptine. Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, tianeptine sodium Tianeptine is reported to act as a selective inhibitor of dopamine uptake . Tianeptine does not have a noted effect on monoamine tianeptine sodium uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation.
TEST ITEM | SPECIFICATION |
Appearance | White or almost white microcrystalline powder |
Solubility | Soluble in the water |
Identification | Should comply |
Related substance | Individual impurity: Not more than 0.1% |
Total impurities: Not more than 0.5% | |
Residue on ignation | Not more than 0.2% |
Loss on drying | Not more than 1.0% |
Heavy metal | Not more than 20ppm |
Assay (on anhydrous basis) | Not less than 99.0% |
Function :
Tianeptine is antidepressant. The animal has the hippocampus pyramidal cells increased spontaneousactivity, and accelerating its function was inhibited after recovery; increase in cortical and hippocampalneurons at sites of5- serotonin reuptake. Tianeptine without following adverse effects: sleep and alertness;cardiovascular system; cholinergic system ( without anticholinergic symptoms ); drug craving
Package : 100g/bag, 500g/bag, 1kg/bag,or at customer's requirements
Storage: Store in a cool, dry place and keep away from direct strong light.
Shelf Life :2 year
